Tuesday, September 30, 2008

Mesothelioma - A Blunder If Not Diagnosed

Mesothelioma is just one of the diseases that people can develop after prolonged asbestos exposure. It is a type of cancer that affects the mesothelial cells which cover the outer surface of most of the body's internal body organs. This is caused by the exposure to asbestos which was around quite a lot in certain areas before it was banned. It could have been contracted in a number of ways from simply breathing it in to picking it up second hand from other people's clothing, hair or skin.

Mesothelioma can take various different forms and can develop in the tissues covering the lungs or abdomen. The most common type diagnosed is pleural mesothelioma which affects the tissues lining the lungs, called the pleura. Fortunately, it is unusual for this disease to spread to other parts of the body. When it does, it doesn't usually cause any problematic symptoms.

Most people who develop mesothelioma will have worked in jobs where they inhaled asbestos particles. The most commonly affected trades were dockers, roofers, plumbers, electricians, shipyard workers and power station workers. However, it is possible for someone to contract the illness even if they have never had direct asbestos exposure. For example, family members may have breathed in the dust particles from the clothing of someone who worked with it.

There are various different symptoms that people can look out for if they know there is a chance they could have mesothelioma. Shortness of breath, a prolonged cough, chest pain, weight loss, abdominal swelling and fever are just some of the signs to look out for. These symptoms may not start showing until 20 to 50 years after asbestos exposure, however which is why many people don't realize what it is at the time.

Diagnosing mesothelioma can be very difficult because the symptoms are similar to many other conditions. For this reason it is extremely important that doctors are made aware of any history to asbestos exposure so they know what to look out for. In order to make a proper diagnosis, a physical examination, a chest x - ray and lung function tests will be performed in order to see if there is any pleural thickening, which is common among those who worked around asbestos. If anything suspicious is found a biopsy will be performed so that a diagnosis can be confirmed and treatment can begin.

Many people have enlisted the help of an asbestos lawyer in order to claim compensation against asbestos manufacturers. The first lawsuit was in 1929 and since then people have successfully won billions of dollars from these companies who neglected to implement safety measures to protect workers against exposure. Mesothelioma Attorneys often take some good percentage of the compensation so watch out before you go ahead and hire any one.

Next Door Mesothelioma

Peritoneal mesothelioma, the rarer of the two forms, can lead to swelling, abdominal pain due to fluid buildup in the abdomen cavity, weight. The other more common pleural mesothelioma symptoms include chest pain and difficulty breathing. Other symptoms often noted among patients include weight loss, fever, cough and night sweats. Also occasionally a patient may be diagnosed with pleural mesothelioma before any symptoms manifest.

A misdiagnosed disease is often an opportunity for the disease to grow in the body. The only way to diagnose mesothelioma is to take a series of tests to discover if the disease is present. A common minimum link to determine the disease is finding the patients proximity to asbestos related environment for 15 - 50 years. If so then image scans can help diagnose the disease. Commonly these include taking a chest x-ray which will show a picture of the lungs to determine if there are any abnormal changes.

A CT scan, computer tomography, is a type of x-ray that uses a computer rather than film to display its images. It can be used to show three-dimensional representations of the relevant parts of the body.

The final type of imaging that may be used is an MRI scan, or magnetic resonance imaging. In an MRI, magnetism is used in conjunction with the computer to create clear images of your body.

If your doctor finds an unusual mass during the imaging process, they are most likely going to take a tissue sample (biopsy), or draw fluid from it to determine what type of tissue it is. Typically a needle is used to draw a small amount of fluid from the tissue. If the results are not able to rule out the condition completely, the next step would normally be to insert a small tube which is attached to a camera and to take a small piece of the tissue remotely. In some cases a more extensive surgical procedure may be needed in order to get a good sample of the tissue. The extreme complicated nature of the disease and fatal nature of the disease often arouses fear in a patients mind.

Lung Cancer Treatment -- Photodynamic Therapy Offers a Safe Alternative

Photodynamic therapy (PDT) is one of the newer lung cancer treatment options available today. Lung cancers are sometimes inoperable, particularly when they are situated in the bronchi or trachea. Similarly, cancers that have spread from other parts of the body to the bronchi cannot be removed surgically. In such cases, photodynamic therapy offers a safe and effective treatment option.

In a best-case scenario, PDT is used as a curative therapy that can eliminate the cancer completely. In many patients, PDT is employed as a palliative lung cancer treatment meant to provide relief from symptoms even though it does not cure the cancer.

Photodynamic therapy can effectively relieve symptoms like breathing difficulties from obstructions in the bronchi or trachea. In some patients, tumors block the airways and can cause coughing, breathing difficulties, pneumonia and bleeding. PDT may be used in such cases depending on the location, size and stage of the tumor.

PDT destroys cancer cells using a laser. To ensure that only cancerous cells are destroyed, a special drug is used to make the cancer cells more sensitive to this treatment while leaving normal cells intact.

There are three steps involved in the process of lung cancer treatment using PDT. In stage one, a drug called photofrin is injected intravenously. This drug has the property of making body cells very sensitive to light. Normal, healthy cells eliminate photofrin, but cancerous cells are unable to do so and the drug is retained in such cells.

In the second stage of PDT, about forty to fifty hours after the injection is given, a flexible tube is inserted into the bronchia. This tube contains a red laser of low intensity. The cancer cells exposed to this laser are destroyed.

In the third and final stage, about two days after the laser light exposure, a bronchoscopy is done to get rid of the dead cancer cells and mucus from the bronchi or trachea.

A patient can benefit from photodynamic therapy only if his or her cancer is situated in a location that is accessible to a bronchoscope. Also, the tumor must be large enough so that the bronchoscope can easily detect it. This means that some cancers like those located outside the bronchial passages cannot be treated with PDT.

Lung cancer treatment with PDT offers almost no dangerous side effects, unlike other treatment methods. Photosensitivity is about the only side effect that lasts for a while. Since photofrin makes cells sensitive to light, the patient may experience heightened light sensitivity for a period of four to eight weeks after the treatment.

During this time, even normal exposure to sunlight can result in severe sunburn. For this reason, patients who have undergone PDT are advised not to venture out into the sun for about eight weeks after their lung cancer treatment. In contrast to photodynamic therapy, major surgery done to eliminate lung cancer usually poses much greater risks.

Many tumors that are inoperable because of their location are prime candidates for treatment with PDT. When used as a palliative, this type of lung cancer treatment offers almost immediate relief.

Sunday, September 28, 2008

INNOVIVE Pharmaceuticals Begins Enrollment in Phase I Study of INNO-305 Peptide Immunotherapy in AML, MDS, Mesothelioma and Non-Small Cell Lung Cancer

NEW YORK -- INNOVIVE Pharmaceuticals, Inc. (OTCBB:IVPH), a biopharmaceutical company headquartered in Manhattan, announced today that a Phase I clinical trial investigating INNO-305 in acute myelogenous leukemia (AML), myelodysplastic syndrome (MDS), mesothelioma and non-small cell lung cancer (NSCLC) has enrolled its first patient. The trial is being conducted by Lee Krug, M.D., of the Thoracic Oncology Service, and Peter Maslak, M.D., of the Leukemia Service at Memorial Sloan Kettering Cancer Center in New York.

The study is an open label fixed dose trial and will study the safety, tolerability, pharmacokinetics and preliminary efficacy of INNO-305. The vaccine will be tested in patients with hematologic malignancies and solid tumors for which there is evidence of WT1 expression.

INNO-305 was invented by David A. Scheinberg, M.D., Ph.D., Chairman of the Molecular Pharmacology and Chemistry Program at Memorial Sloan-Kettering Cancer Center. Dr. Scheinberg notes that pre-clinical research has demonstrated promising characteristics with significant potential as a cancer therapeutic.

INNO-305, a WT1 peptide therapeutic vaccine, is unique among WT1 peptide immunotherapies because of its ability to stimulate both CD8 and CD4 T-cells. It is believed that stimulating both types of T-cells may result in a more robust and ubiquitous immune response. As an added measure, INNO-305 utilizes an approach in which the wild-type WT1 peptide sequences are altered to improve the ability of the drug to activate T-cells.

Clinical studies with other WT1 peptide immunotherapies have already shown promising results in patients with AML and other cancers. By using modified, non-natural peptides that stimulate both CD4 and CD8 T-cells, INNO-305 may offer an advantage over other WT1 peptide immunotherapy approaches.

"With the initiation of the INNO-305 trial, Innovive now has three clinical stage oncology compounds. We have taken significant strides over the last twelve months and continue to build a meaningful oncology portfolio," said Steven Kelly, President and CEO, Innovive Pharmaceuticals.

Innovive licensed worldwide development rights for INNO-305 in January 2006 from Memorial Sloan-Kettering Cancer Center in New York.

About INNOVIVE Pharmaceuticals

Innovive Pharmaceuticals, Inc. is a public biopharmaceutical company headquartered in New York, N.Y. The company's mission is to acquire, develop and commercialize novel therapeutics addressing significant unmet medical needs in the fields of oncology and hematology. For additional information visit www.innovivepharma.com.

This press release contains forward-looking statements that involve risks and uncertainties that could cause INNOVIVE's actual results to differ materially from the anticipated results and expectations expressed in these forward-looking statements. These statements are based on current expectations, forecasts and assumptions that are subject to risks and uncertainties which could cause actual outcomes and results to differ materially from these statements. Among other things, there can be no assurances that any of INNOVIVE's development efforts relating to its product candidates will be successful. Other risks that may affect forward-looking information contained in this press release include the possibility of being unable to obtain regulatory approval of INNOVIVE's product candidates, the risk that the results of clinical trials may not support INNOVIVE's claims, INNOVIVE's reliance on third party researchers to develop its product candidates and its lack of experience in developing pharmaceutical products. These and other risks are discussed in INNOVIVE's Registration Statement on Form 10 filed with the SEC. INNOVIVE assumes no obligation to update these forward-looking statements, except as required by law.

Mesothelioma Lawyer Attorney.com Launches Industry First Directory of Mesothelioma Lawyers, Mesothelioma Attorneys and Mesothelioma Doctors

LOS GATOS, Calif. -- Mesothelioma Lawyer Attorney.com today launched the industry's first directory of mesothelioma lawyers, mesothelioma attorneys and mesothelioma doctors, designed to help victims of mesothelioma find qualified legal and medical help.

Mesothelioma, a form of cancer that is almost always caused by previous exposure to asbestos, causes malignant cells to develop in the lining around the lungs, heart, and abdominal cavities. Most people who develop mesothelioma cancer have worked careers where they inhaled asbestos dust, or have been exposed to asbestos particles and fibers in other ways, such as by home renovation or by washing the clothes of a family member who worked with asbestos.

The mesothelioma lawyer, attorney and doctor directory also provides members of the legal and medical field the opportunity to reach and aid more victims of mesothelioma. The directory's top ranking on Google, MSN, Yahoo and other major search engines, ensures that mesothelioma lawyers, attorneys and doctors listed in the directory are seen by the website's 3,000 daily visitors.

"Thank you for helping me find a good mesothelioma attorney," said recent website visitor George Trent. "After a short phone consultation, they came all the way out to my house in New Jersey and showed me exactly how they were going to help."

If you or someone you love is suffering from mesothelioma cancer, you have certain legal rights that you need to know about. One way to take a stand against the asbestos industry, that put their profits ahead of your health, is to take legal action against them. You are entitled to financial compensation for your pain and suffering, but if you hesitate, you may lose your chance for justice due to your states' statute of limitation laws.

Expression of Activated and Latent Signal Transducer and Activator of Transcription 3 in 303 Non-Small Cell Lung Carcinomas and 44 Malignant Mesotheli

* Context.-Signal transducer and activator of transcription 3 (STAT3) is constitutively activated in diverse human cancers and plays a critical role in tumor cell survival, proliferation, migration, invasion, angiogenesis, and inhibition of apoptosis. The phosphorylated active form of STAT3 (pSTAT3) mediates its effects via nuclear transcriptional activity. However, it was recently observed that the nonphosphorylated, cytoplasmic, inactive form of STAT3 is involved in cell motility and consequently tumor invasion. It appears that, although STAT3 is not absolutely required for tumor formation, tumors that develop in the presence of STAT3 become dependent on its expression for their survival, making it a potential therapeutic target.

Objective.-To investigate the possible utility of STAT3 as a future therapeutic target in non-small cell lung carcinoma (NSCLC) and malignant mesothelioma (MM).

Design.-Immunohistochemical expression of MIB-1, STAT3, and pSTAT3 was assessed in 303 NSCLC and 44 MM archival cases.

Results.-A more conspicuous expression of inactive STAT3 (91.44% in NSCLC and 79.5% in MM cases) was present compared with the nuclear activated form pSTAT3 (60.53% in NSCLC and 61.4% in MM cases). MIB-1 did not correlate with the expression of STAT3 or pSTAT3.

Conclusions.-The strong expression of cytoplasmic inactive STAT3 in NSCLC and MM cases implies a major role for STAT3 in tumor motility, invasion, and metastasis via a nontranscriptional pathway. We conclude that STAT3 and pSTAT3 are up-regulated in a high percentage of NSCLCs and MMs, regardless of tumor type, age, sex, smoking status, stage and grade of tumor, or survival, providing a basis for therapeutic intervention.

(Arch Pathol Lab Med. 2007;131:1350-1360)

Signal transducer and activator of transcription (STAT) proteins are latent cytoplasmic molecules (Figure 1, A), which are activated in response to many cytokines (eg, interleukin 6) and growth factor signals1 (eg, epidermal growth factor, platelet-derived growth factor, and vascular endothelial growth factor) (Figure 1, B) and have the ability to transduce a signal from a cell surface receptor into the nucleus and promote the transcription of specific genes. Although these transcription factors are often not mutated themselves, their overactivation by mutations in other genes leads to the gene expression changes that are hallmarks of malignant disease. The activation of cytoplasmic, latent STATs is dependent on tyrosine phosphorylation (Figure 1, C), which induces dimerization (Figure 1, D) via interaction between 2 STAT molecules.2 Many tyrosine kinases including Janus kinases (Figure 1, E) and receptor tyrosine kinases (Figure 1, F) can mediate phosphorylation (activation) of STAT proteins. Activated STATs are translocated to the nucleus (Figure 1, G), where they bind to consensus sequences on the promoter of target genes and activate their transcription2 (Figure 1, H). In normal cells, STAT tyrosine phosphorylation is transient, lasting from minutes to several hours, and the tyrosine dephosphorylated STAT proteins are shuttled back to the cytosol from the nucleus3 (Figure 1, I). However, in numerous cancer-derived cell lines or in primary tumors, STAT proteins are persistently tyrosine phosphorylated.4 There are at least 6 STAT proteins involved in this complex signaling pathway. Among these STATs, STAT3 stands out by its constitutive activation in most human neoplasms.2,5 Activation of STAT3 is detected in solid tumors (breast, lung, head and neck [squamous cell carcinoma]; ovarian and pancreatic cancers; melanoma; hepatocellular carcinoma; cholangiocarcinoma; and prostate, endometrial, and cervical cancers) as well as in hematopoietic tumors (acute myelogenous leukemia, multiple myeloma, Hodgkin disease, non-Hodgkin lymphoma, B-cell lymphoma, and cutaneous T-cell lymphoma).1,2,5-7 It has been demonstrated that STAT3 in tumor cells promotes cell growth and cell survival through the transcriptional up-regulation of target genes7 (eg, c-myc, bcl-xL, bcl-2, cyclin D1, VEGF), whose products promote cell proliferation, cell migration, invasion, angiogenesis, and inhibition of apoptosis8 (Figure 1, J). It has been described that the inhibition of STAT3 function in non-small cell lung carcinoma (NSCLC) cells increases apoptosis of these cells, suggesting that STAT3 is necessary for their survival.9,10 It is believed that STAT3 mediates its effects through the nuclear localized transcriptional activity. However, evidence for a cytoplasmic nontranscriptional role for STAT3 in cell motility and consequently in tumor invasion has accumulated and a direct effect of nonphosphorylated cytoplasmic STAT3 on cell motility through a nontranscriptional protein interaction mechanism has been recently demonstrated11,12 (Figure 2, A through E). STAT3's control of cell motility, in addition to its cell proliferation-promoting and antiapoptotic activities, directly contributes to its role in tumorigenesis and tumor progression.8 In addition, STAT3 has been described as a component of focal adhesions (sites of cell contact with the extracellular matrix) that may contribute to the invasiveness of cancer cells13 (Figure 2, C). There is an unmet need to develop new treatment modalities for lung cancer. Molecular targets for treating cancer have been particularly difficult to develop because of the multiplicity of genetic mutations in cancer cells. Targeting 1 mutation at a time appears to be ineffective. Recently, however, it has been realized that genetic mutations in cancer often converge on central regulators: the transcription factors.5 New research is now pointing to STAT3 as a promising target for the development of a global anticancer therapy agent. To investigate the possible utility of STAT3 as a future therapeutic target in NSCLC and malignant mesothelioma (MM), we evaluated the presence of the inactive form of STAT3, the active phosphorylated form of STAT3 (pSTAT3), and the proliferation marker MIB-1. In NSCLC cases, the results were correlated with age, sex, grade, stage, smoking status, and survival.

Friday, September 26, 2008

Lung Cancer Prevention

Is there anybody alive in the United States today who does NOT know that smoking tobacco is the leading cause of lung cancer? Probably not. To avoid that knowledge, you'd have to live under a rock. There isn't any way to absolutely prevent lung cancer, but never smoking or quitting smoking is one way to significantly lower the risk.

There are, however, other risk factors associated with lung cancer that we have no control over at all. There are environmental causes, that we just can't do anything about. Such things as asbestos, radon, arsenic, chromium, nickel, tar, and soot that are commonly found in the workplace can cause lung cancer in people who have never smoked. The United States and other countries are working to control these substances in the workplace and some progress has been made - not enough, but some.

Just plain old air pollution is another cause of lung cancer. The incidence of lung cancer is higher in cities where air pollution is worse.

Studies have shown that a good diet that is high in fruits, vegetables, and whole grains and low in saturated fat, red meat, and preservatives does lower the risk of contracting lung cancer.

Abstaining from alcohol consumption altogether is another way to lower your risk of contracting lung cancer.

Research shows that people who are physically active have at a lower risk for developing lung cancer than those who are sedentary - and this is true even after taking cigarette smoking into account.

Using drugs, vitamins, or other agents to try to reduce the risk of, or delay the development or recurrence of, cancer is called chemoprevention. This is an area that scientists are studying, and there are clinical trials in progress that are testing both natural as well as man-made drugs, but it has not become a standard treatment or therapy.

Mesothelioma Law Firm

There are very many mesothelioma law firms around and the main reason why they specialize in these particular cases is the huge return the cases can fetch. Others might be genuinely out there for the compassion of mesothelioma victims but, they are limited. Firstly though, mesothelioma is a cancer that affects the protective lining of the heart, lungs and abdomen. The known cause of mesothelioma is asbestos exposure. This is a natural mineral that has very many industrial uses mainly because of its heat and fire resistant qualities. It is known to lodge in the system when inhaled where it can stay there for many years where finally it causes the emergence of a disease. It has no scent and its fibers in the air are microscopic. Therefore mesothelioma law firms are relevant in the following way.

Firstly, the companies that employ workers to work exposed to asbestos have a case to answer because they have a moral duty to inform workers. They are therefore directly responsible for the illness in their worker. When a mesothelioma victim decides to file a suit against the company, they need to have the representation of good lawyers who can be found in a good mesothelioma law firm. Some of the workers who might be at risk to asbestos exposure include miners, millers, shipyard workers, building construction workers and others. With the serious realization of the dangers posed by asbestos, strict legislations have been put in place to ban certain types of asbestos and also there are restrictions on the amount of asbestos exposed to workers.

Also, workers who are close to asbestos have protective cloths and equipment to protect then from the substance. When they leave work, most workers take a shower and change cloths to avoid contaminating their families. When you suspect that you might be suffering from mesothelioma, you need to visit a doctor for a diagnosis. If you have the disease, you need to take time and look for a reputable mesothelioma law firm which will have good lawyers. They should have some experience in this kinds of cases. They should not live very far from where you are located so that you can reach them with minimal cost. The mesothelioma law firm should be legal and licensed to practice law in your particular state or country. They should give you more information on the cases they have been able to resolve.

On the internet, you will find very many mesothelioma law firms advertising themselves and you should not just take them at face value. You need to contact them and visit their offices to get a first hand feel of what they are all about. Many firms will be literally fighting for your case and you do not have to hire the ones who are first make a perfect pitch. Firstly, you need to know that they can represent you and win the case. You should discuss on the attorney fee before you hire the lawyer from the law firms. Usually, the most common way of payment is through a contingency basis and this means that they will be paid when you win the case. There is no doubt that with the right lawyers on your side, you are certain to get your deserved justice will be served.

Important Facts About Lung Cancer

According to the American Cancer Society, lung cancer is still one of the most prevalent forms of cancer today. Even after all of the thousands of antismoking campaigns and a huge decrease in the number of smokers, it is expected that there will be more than 215,000 new cases diagnosed this year, and there will be nearly 162,000 deaths.

In 1991 (the latest year that I could find statistics for), 27% of Americans were smokers. That compares to 29% in 1987 and 44% in 1964. The decrease is because of more people quitting the smoking habit, and NOT because of fewer people starting the smoking habit. It's obvious that all of the efforts to prevent people from becoming smokers have not been successful.

Cigarette smoking is considered the number one cause of the disease. There are substances in smoke that cause damage to lung cells. Because of this, smoking cigarettes, pipes, or cigars does cause lung cancer, and this is why it is also true that secondhand smoke can cause lung cancer in nonsmokers. The more often a person is exposed to tobacco smoke, the greater the risk of lung cancer.

However, cigarette smoking is not the only cause. Researchers have also determined that exposure to radon is a big risk factor for developing lung cancer. Radon is found in mines as well as in various parts of the country in the rock and soil. Radon is a radioactive gas that is colorless, odorless, and tasteless.

Exposure to asbestos is another cause of lung cancer. People who work at such jobs in the construction and chemical industries are most at risk for exposure to asbestos that can cause lung cancer.

A family history of lung cancer, even in people who have never smoked, also creates a higher risk for developing the disease.

Wednesday, September 24, 2008

Mesothelioma - Symptoms of Mesothelioma Cancer

Do you know what the most common symptoms of mesothelioma cancer are? Well, the most common symptoms are shortness of breath and pain in the chest. These symptoms occur due to a buildup of fluid in the pleura, what is known as Pleural Mesothelioma. However there are other symptoms of Peritoneal Mesothelioma, those may include weight loss, abdominal pain and swelling, this is due to an accumulation of fluid in the abdominal cavity.

Peritoneal mesothelioma may include other uncomfortable symptoms too, such as bowel obstruction, blood clotting abnormalities, anemia and fever. However these symptoms can appear before if malignant cancerous cells have spread beyond the mesothelium to other parts of the body, and other symptoms such as trouble swallowing, pain, and swelling of the neck or face may appear.

Mesothelioma or other less serious conditions may caused these symptoms, therefore the importance of going to a doctor if you feel any of these symptoms, because only an expert like him can make a correct diagnosis.

Mesothelioma cancer rate has increased over the past 20 years and although this disease is not as common as other cancer pathologies, the number of new diagnosed cases in the United States has risen up to 2,000 per year.

According to experts the major risk factor for developing Mesothelioma lies in working with asbestos, so if you are a asbestos worker remember following the U.S. Occupational Safety and Health Administration recommendations in order to reduce your risk.

Asbestosis is an Asbestos Related Disease and May Be Considered As an Occupational Disease Too

A benign pleural disease is an asbestos-related disease which still has something of mystery to experts, since they don't know why some asbestos workers get one of several benign diseases of the pleura while others are not affected by the terrible consequences of Asbestos.

The pleural cavity is the space between the lungs and the chest wall, which has an small amount of pleural fluid in the normal non-diseased state. The pleura is the epithelium that lines this cavity. Asbestos fibers can reach this part of the body.

The parietal pleura, which is connected to the chest wall, is highly sensitive to pain. Meanwhile, the visceral pleura, which is connected to the lung and other visceral tissues, is not sensitive to pain.

The function of pleura and pleural fluid is to reduce friction between the lungs and the inside of the chest wall during breathing. Asbestos fibers make difficult this. A benign pleural condition usually does not progress and is not fatal. These conditions include pleural plaques, diffuse pleural fibrosis and benign pleural effusion.

Pleural effusion occurs when fluid accumulates in the pleural space and compresses the lungs.

Pleural plaques is a discrete fibrous or partially calcified thickened area which can be seen on x-rays of individuals exposed to asbestos. Benign pleural diseases appear various years after the exposure to asbestos and according to some experts cause little or no trouble, since some people do not even show symptoms. However, having a benign pleural disease may be the sign of developing asbestoses or another asbestos-related disease later.

WSIB - The Importance of Knowing Your Rights If You Have a Asbestos-Related Disease

Are the rates of asbestos disease increasing in the U.S? The answer is definitely yes.

Asbestos-related diseases are increasing in the United States and in some other countries, and this is because asbestos workers were exposed to this mineral, which is the main risk factor for developing the disease. The Workplace Safety and Insurance Board (WSIB) helps you to find out if you are entitled to compensation if you worked and were exposed to asbestos.

This is important, because when you are sick you do not have time to think of your disease causes, since you never thought of being ill with pain and even with so much danger to your health.

In Ontario, Canada, exists a Workplace Safety and Insurance Board (WSIB) that oversees your state's workplace safety education and training system, provides disability benefits, monitors the quality of health care, and assists in early and safe return to work.

The most exposed workers to the risk of developing an asbestos-related disease are power plant workers, asbestos and talc miners, shipyard workers, auto break mechanics, demolition workers, pipe fitters, insulation workers, boilermakers and workers who make products which contain asbestos, such as firebricks, fire-retardant paint and asbestos cement.

The most common asbestos-related diseases are asbestosis, mesothelioma, benign pleural diseases, pleural plaques and lung cancer.

A cure does not exist for most of the above mentioned diseases, but there are treatments such as chemotherapy or radiotherapy, as for other types of cancer pathologies. There are also different ways of prevention the high risk of inhaling asbestos fibers when you work with this material.

Monday, September 22, 2008

Mesothelioma - Treatments For Mesothelioma Cancer

Mesothelioma cancer is currently treated through three treatments, depending on the cancer location, the disease stage, and the patient's general health and age. These treatments are surgery, chemotherapy and radiation therapy, which sometimes are combined to fight the disease in so far as possible.

In a surgery, one of the most common treatments for mesothelioma, the doctor removes part of the lining of the abdomen or the chest and some tissue around it. In a pneumonectomy, the doctor may also remove one lung when the patient has pleural mesothelioma or cancer of the pleura. In other surgical procedure, the doctor may also remove part of the diaphragm, the muscle below the lungs that helps with breathing. Through these procedures, the medical specialist shall try to excise tumourous tissue arising from this cancer disease. As these operations will reduce the patient's respiratory capacity, the surgeon will evaluate the patient's ability to function after a lung tissue removal, before performing a pneumonectomy.

Another method to fight Mesothelioma is chemotherapy or the use of anticancer drugs to kill cancer cells throughout the body. These drugs are given to the patient by an intravenous procedure, an injection into a vein. Currently, experts are studying the effectiveness of intracavitary chemotherapy or the possibility of giving chemotherapy straight to the chest or abdomen.

Radiotherapy or radiation therapy is the use of high-energy rays to destroy malignant cells and shrink tumors. It is important to know that this medical procedure attacks the cancer cells only in the treated area. There are two ways of giving this therapy. One, external radiation, in which the radiation comes from a machine, and other, internal radiation, where the cancer cells are found after putting materials that produce radiation into the affected area.

Doctor's way to relieve patient's pain is to use a needle or a thin tube to drain fluid that has built up in the abdominal or chest cavities through a procedure called thoracentesis. When it is from the chest, and paracentesis, when the removal is from the abdomen. The specialists may also give the drugs through a tube in the chest to prevent the accumulation of more liquid.

Mesothelioma Diagnosis

Mesothelioma is the technical name for cancer of the mesothelium.

It can be difficult to diagnose because many of the symptoms are similar to other conditions, like lung cancer.

The first visit you have with your doctor, he'll ask you about exposure to asbestos. Older homes were made of asbestos.

Even though it's hard to detect in its early stages, a doctor can perform a couple of tests. Chest x-ray, CT scan and MRI scan will allow the doctor to do a good diagnose.

A CT scan is used to create detailed images. MRI scan uses magnetism, radio waves, and a computer but does not utilize radiation to create a clear image.

These tests aid the doctor in differentiating between mesothelioma and other lung tumors. And they can also help in determining where the tumor is.

If necessary, a doctor might have to draw fluid to confirm its diagnosis. There are a couple of ways to do it.

First, a doctor can make a small incision to place a flexible tube in the area of the tumor which is called a thoracoscopy. Sometimes, however, a more extensive surgical procedure may be advisable.

Second, a thoracotomy can be done to open the chest to take a tissue sample and to remove most of the visible tumor. Also, a mediastinoscopy may be done to determine what kind of cancer it is.

Then, the tissue samples are looked at under a microscope to determine whether the tumor is a mesothelioma or some other type of cancer.

Mesothelioma - Diagnosis of Mesothelioma Cancer

If you have researched a little, you should know that diagnosis of Mesothelioma cancer is very difficult in many cases, because its symptoms can be associated with other diseases too. Hence patient's medical history is quite important to know, since if there was an exposure to asbestos from the sick person, the risk factors for developing Mesothelioma are greater.

The doctor will order you a physical examination, including chest and abdomen x-rays, and lung function tests. A computerized tomography (CT) or a computerized axial tomography (CAT) scan may be useful, along with a magnetic resonance imaging (MRI).

The CT scan allows a computer x-rays machine to create a series of detailed pictures of inner body areas. The MRI allows to obtain detailed images of areas inside the body through a powerful magnet linked to a computer.

The way to confirm a Mesothelioma diagnosis is a biopsy, in which an oncologist or a doctor specialized in diagnosing and treating cancer pathologies takes a sample of tissue from the patient to examine it under a microscope. The biopsy may be performed in various ways. In a thoracoscopy the name of the biopsy if the cancer is in the chest the doctor makes a small cut through the patient's chest and introduce a tube called thoracoscope to look inside and take tissue samples.

In a peritoneoscopy if the cancer is in the abdomen the doctor makes the same procedure but in the patient's abdominal cavity to obtain tissue for examination.

The stage of the disease is important to know if cancer is metastasized to other parts of the body, and to apply the best treatment for the patient.

The disease will be 'localized' if the cancer is found only on the surface of the membrane, but it will be 'advanced' if it has spread to other parts of the body, such as lungs, abdominal organs, chest wall, lymph nodes.

Saturday, September 20, 2008

Lung Diseases Up Among 9-11 Rescue Workers

People living and working in New York on that fateful day when the Twin Towers came down are becoming ill in growing numbers. World Trade first responders and others are developing chronic coughs, lung diseases and now other cancers caused by breathing the toxic mix of asbestos, dioxine, benezine, and other carcinogens released at and around the site.

Eventually some are likely to develop mesothelioma-a disease specifically related to exposure to asbestos. And some who were there will also begin to develop potentially lethal blood clots. Patients with cancer of all types tend to have a significantly higher risk of blood clotting then the general population. Because of its severity as a disease, scientists decided to try to find out whether patients with mesothelioma also follow that trend.

In a small study in the state of New Mexico the rate of dangerous (thromboembolism) among mesothelioma patients was significantly higher-close to double the rate-among other cancer patients. This is yet another way this disease can kill or disable its victims. If you know someone who may be at risk for mesothelioma, be sure to let them know they should talk to their doctor about the advisability of taking blood thinners (anticoagulants).

There are similarities between the victims of the Towers tragedy and those who've developed mesothelioma as a result of manufacturers who failed to provide adequate warnings and protective clothing and equipment for people working around asbestos. The difference is there will be a far larger public outcry when the consequences to rescue workers at the 9/11 disaster become common knowledge. When you've been the victim of such failures in the private sector, you have to look harder to find a voice on your behalf.

Be sure to find a doctor who understands the need to keep an open mind about diagnosing and treating mesothelioma. And if you've been diagnosed, please don't hesitate to call if you have any questions about your right to file a lawsuit for compensation or other damages for being exposed to asbestos at work. Mesothelioma is a killer disease and you and your family deserve to understand your legal rights.

Kent Cigarettes Filters Used Deadly Crocidolite Asbestos

Incredible as it may seem - because the dangers of asbestos were already beginning to be known - back in the 50s the P. Lorillard Company was using deadly crocidolite fibers in its Kent cigarette filters. In a review guide on eBay, an asbestos-identifying private consultant writes about the history of the asbestos-laden "micronite" filter used on Kent cigarettes between 1952 and 1956. And the U.S. government website notes that anyone who smoked a pack a day of Kent cigarettes between 1952 and 1956 may have been exposed to as much as 131 million crocidolite structures in a single year.

If you know anyone who was a smoker during this period, you may want to advise them of the danger to which they may have been exposed. Suggest they consult a physician who is an expert at understanding the early signs of asbestosis, lung cancer, and mesothelioma. Early detection can help with treatment and possibly improve quality of life. See below to find information about doctors who understand the complexities of diagnosing and treating mesothelioma.

Perhaps even more interesting was the claim that Kent cigarettes made for the positive health benefits the filter supposedly conferred on smokers. When a large number of workers from the Kent factories making the filters began coming down with those respiratory diseases, the alarm was raised. In 1995 scientists located unopened packages of Kent filter cigarettes date stamped from 1952. They put them through testing with artificial smoking machines that could measure the contents of the smoke. Extensive testing with first puffs and puffs after cigarettes had been put out and relit revealed that crocidolite fibers were present in the filters. They showed that many of the fibers were long enough to be classed as more likely to be carcinogenic and that substantial numbers of those longer fibers were carried directly into the smokers' mouth and lungs.

As time has passed and more and more people are growing sick 30, 40, and 50 years later because of negligent behaviors by corporate entities long ago, our society has begun to realize that advertising can be manipulated to say anything that serves to boost sales, regardless of whether it's based on facts. This is a good thing for public health--though too late for many. We are dedicated to helping assist those who may be suffering from mesothelioma from any cause.

What You Need to Know About Lung Cancer

Lung cancer occurs when cancerous cells develop in the lung's tissue. It is the most common fatal cancer among men and women, and it is the number one killer in the world. Lung cancer has the highest mortality rate out of all the cancers combined. People with risk factors for developing the disease should have regular checkups to determine if they are cancer free.

Family history of the disease can be a warning sign that lung cancer may run in your family and that you should be checked more often. Some risk factors for lung cancer can also include age, sex, or race and are called non-modifiable factors because the person can't change them. Some lesser-known symptoms to watch out for include:

o Shoulder or upper back pain caused by a tumor pressing into the lung lining

o Swelling of the face and neck caused by change in circulation brought on by the tumor

o Having frequent bouts of pneumonia or other lung infections

When tumors press against blood vessels, the fluids cannot travel as well through the body, and these fluids build up in the neck and face and often times the hands and feet as well. Having frequent periods of lung infections or pneumonia can also be a sign of lung cancer as the cells of the tumor trap and hold bacteria.

There are two types of lung cancer - Non-small cell and small cell. Non-small cell cancer is usually associated with people who smoke and is the most common form of diagnosed cancer. Small cell lung cancer - or oat cancer - is rarer, but is also caused by smoking. Non-small cancer is more common and spreads much slower than small cell cancer. Three main types of this cancer are named for the cells where they tend to develop. These are Squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Small cell lung cancer tends to grow and spread much more quickly than non-small cancer and can quickly spread to other areas of the body. Both types of cancers react to treatments in different ways.

Some substances that can cause lung cancer are familiar to you while others may come as a surprise. Cigarette smoking is one of the causes. How often have you heard that over the years? It is far more likely that someone who smokes will develop lung cancer than someone who doesn't smoke. The age at which the person began smoking, and the length of time they've been smoking are also factors in the development of the disease. Even people who don't smoke themselves can be exposed to the second-hand smoke and develop lung cancer over time. Some other substances that can cause lung cancer include Radon exposure and Asbestos exposure.

It's very important to follow up with your doctor if you suspect that you may have some symptoms. The sooner the disease is discovered and treatment is begun, the sooner you'll be well again. Regular checkups can make sure that any cancer is caught in the early stages and can be treated quickly and effectively with a variety of treatments. Physical exams, x-rays, and blood or urine tests may be required to check thoroughly.

Thursday, September 18, 2008

Lung Cancer Through the Quad Transfer

Lung cancer, not only in the primary site continue to grow and spread, but also often through the lymphatic and Xuelu transferred to the local lymph nodes and other body organs. The incidence of lung cancer more often concealed, early often no obvious symptoms, easily overlooked, and even some long-distance transfer of patients has occurred, is still not confirmed, the understanding of the characteristics of the transfer of lung cancer, lung cancer diagnosis and treatment will also be Helpful.

Direct spread

Lung cancer from bronchial occurred along the infiltration of bronchial wall, directly to the proliferation of proximal or distal end, to be invaded trachea eminence plane, or air to the lungs through bronchial wall infiltration growth in real terms, and further up to mediastinal pleura . The latter can lead to the cultivation of the two pleural proliferation, pleural thickening, as if the corpus callosum. Could be worse transgression and chest wall and diaphragmatic, or to the esophagus and the pericardium.

Lymphatic metastasis

Lung cancer at an early stage is likely to occur lymphatic metastasis. General small cell carcinoma of the transfer earlier than squamous cell carcinoma and. First found in lymphatic metastasis of the lung lymph nodes, hilar lymph nodes, trachea and bronchi adjacent lymph nodes. This may be to mediastinal lymph nodes (which is the guideline for long-distance transfer) autopsy cases of lung cancer about half that peritoneal metastasis.

Xuelu transfer

Xuelu transfer of common lung cancer, often caused systemic result of extensive transfer of death, the mortality rate was 92%. Especially those that are not differentiated small cell lung cancer such as cancer, the cancer cells may occur early Xuelu transfer, and then later adenocarcinoma and squamous cell carcinoma. Lung cancer transferred to remote organs, not from lung cancer is often the primary site Xuelu transfer, but through the mediastinum into the metastasis venous circulation Yan returned to the lungs. Therefore, in general there is no transfer of early lung cancer, lung metastasis is not uncommon. According to the autopsy materials and lung cancer of the lung metastases found only 10 percent of the cases, but to make sure it is transferred from the Xuelu mediastinal lymph nodes from, or from the more common internal organs to shift from the Xuelu, it is difficult.

Cultivation of transfer

Body cavity of the organ tumors spread to the organ surface, the tumor cells can be exfoliated and, like sowing, planting in the body cavity and body cavity of the organ on the surface, forming the majority of the transfer. This method known as the transfer of duty of the transfer or sowing, more than occurred in the abdominal or thoracic organ cancer. Organs of cancer, such as the invasion of gastric cancer and gastric damage serosa, Ke Zhongzhi to the omentum, peritoneal, abdominal organs in the face of even the surface of ovarian, etc.. Lung cancer is often in the chest with a wide range of cultivation of the transfer. Serous cavity of the cultivation of each shift with serous bloody fluid, it is because subserosal lymphatic or vascular thrombosis was resistance, resistance to cancer or serous stimulus to the permeability of capillary A result of increased leakage increased, and because blood vessels were small cell carcinoma of the destruction it caused bleeding. Suction fluid for cytology see often available on the cancer cells. It is worth noting that surgery could also result in cultivation.

Top 5 Signs of Lung Cancer to Long-Term Smokers

Usually in the early of lung cancer, there are no special symptoms. Only when lung cancer is developed to a certain stage, there will be some symptoms, including cough, blood in sputum, fever, chest pain, chest tightness and some other respiratory symptoms. Lung cancer may easily be overlooked or be treated as pneumonia, so to cause the delay condition. People above 40 years old especially have a long history of smoking or passive smoking, must have a regular physical examination annually. People should also be vigilant immediately for medical treatment when the following performance appears, which is helpful to find lung cancer in time.

1. Chronic Cough

Tumour stimulates the trachea, will often lead to irritating cough. This cough has nothing to do with the season, time or medication. This is the most common symptoms of lung cancer, and about 2/3 of the patients have this symptom. People must be prudent when there is a cough of unknown causes. Some people who has a long-term chronic cough must go to see a doctor when he feels that the cough situation has changed.

2. Blood In Sputum

Tumour causes cell necrosis and broken of capillaries, a small amount of bleeding mixed with sputum and so this Intermittent or persistent symptom appears. About 50% of the patients with lung cancer have this symptom.

3. Chest Pain

About 30%-40% of lung cancer patients will appear chest pain, generally not keen intermittent chest pain, mainly shown as stuffy pain or vague pain with uncertain location, may continue from several minutes to several hours.

4. Repeated Fever

Bronchial cavity was blocked by tumor, poor drainage may lead to fever. The body temperature is generally under 38 degrees. Treat early with antibiotic, the body temperature can return to normal, but easy to relapse.

5. Chest Tightness And Shortness Of Breath

Tumor will affect the normal lung function, and will lead to chest tightness and shortness of breath when people are tired, which is the most obvious in central lung cancer.

Asbestos in Children's Toys

Asbestos in toys. Asbestos in duct tape, in spackle, and sealer. In December 2007 asbestos was found in the childrens toy, "The CSI Fingerprint Examination Kit" as well as two brands of children's play clay. Where else can asbestos be found? Vinyl flooring, duct wrapping on heating and air conditioning systems, roof shingles and home siding, ceilings (where it has the textured, bumpy look). EEEK, I grew up with that. Wall and attic insulation and sheet rock compound to name a few.

O.K., some of the products mentioned were produced between 1920 and 1970. However, the shocking truth is that asbestos is still being used in consumer products today, in 2008! Do you do gardening? If so, NEVER use a product with vermiculite in it. Vermiculite is a mineral that is usually contaminated with asbestos. Vermiculite has been used in potting mixes, brake pads, acoustic tiles, and insulation.

What about collecting antiques? Coffee pots, irons, toaster and blow dryers have contained asbestos. One blow dryer called the " Rocket Blower" was used in beauty salons until it was recalled in 1979.

Talc, yes the stuff in baby powder and cosmetics could contain asbestos. On June 22, 2000 in the Seattle Post Intelligencer, Andrew Schneider's article ran about the asbestos contamination in Talc.

How do we know that our baby powder, ceilings and toasters do not contain asbestos? We don't. Many homes built before 1980 contain asbestos. It can be in the vinyl floor tiles, ceiling tiles, roof shingles, insulation, pipe cement, and joint compound. Some newer houses may also contain asbestos.

Asbestos can be found in many public places. Two of our recent national tragedies come to mind...9/11 and Hurricane Katrina. When the World Trade Center collapsed, it sent a large amount of asbestos dust into the air. The first responders and citizens breathed in that dust. Many folks have developed lung problems, and some have already died. Hurricane Katrina clean up efforts had to be halted due to the presence of asbestos.

Why is existence of asbestos such a big deal? It is a big deal because thousands and thousands of people have died from asbestos exposure. Asbestos fiber's are breathed in when mixed with dust. The fiber are like little razors. They can cause significant scarring of the lung tissue leading to a disease called asbestosis. Breathing asbestos fiber's can also lead to a form of lung cancer called mesothelioma. The ONLY known cause of mesothelioma and asbestosis is breathing in asbestos particles. Scientists have stated that NO amount of asbestos exposure is safe.

So why? Why do products still contain asbestos? Why isn't there more information available for the public to learn about the danger of asbestos? If you are outraged by this, you may click on the link to my site, and sign the online petition to completely eliminate asbestos in all products.

Monday, September 15, 2008

How to Choose a Mesothelioma Lawyer?

Mesothelioma is an occupationsl disease. Exposure to asbestos at the workplace is the single most important risk factor for developing mesothelioma. In the era when safety measures were often deficient, workers were constantly exposed to asbestos fibers and many of them developed the disease. Mesothelioma develops some 40-60 years after exposure and is thus common in the senior citizens who have worked in places known to have asbestos in the ambient environment. Compensations and lawsuits are common and are justified where there were gross violations in safety measures. The manufacturers and even distributors knew for decades that asbestos was hazardous, but they did not warn people of those hazards. As a result, a patient has the right of recovery against those manufacturers who can help pay the costs of treatment and provide compensation for the resultant pain and suffering.

No amount of monetary benefits can compensate the suffering but at least the compensation can take care of the medical expenses involved. Any person affected directly or indirectly is eligible for compensation.

Filing a mesothelioma lawsuit is a long and tedious process. As soon as a diagnosis has been made, it is critical to get hold of a qualified mesothelioma attorney to file claims. It is better to file a suit with the help of attorneys who are experienced in these issues. They have done the hard legwork and groundwork and as such can help speedier processing of the claims. All said and done choosing a mesothelioma attorney is a personal decision and best left to the patient and his or her relatives.

The following questions can help make a good decision regarding mesothelioma lawyers and firms.

1. How long has the firm been handling these type of cases?
2. How many cases are being handled currently?
3. How many cases have been handles successfully in the recent past?
4. Will a law firm work on your case or refer it to another law firm? If referred what are the credentials of the referred law firm?
5. How many cases have been taken to trial and what have been the nature of the verdicts?
6. In the event of an appeal are there qualified lawyers in the firm who handle appellate and related legal issues?
7. What is the track record for the firm in handling appealed cases successfully?

The Martindale-Hubbell Legal network is a good point to begin search for mesothelioma lawyers and firms. A simple search on a search engine will give further details. The Oklahoma Bar Association has put out excellent guidelines regarding choosing an attorney. They state that "Selecting a lawyer is a personal matter. You must judge which particular attorney will be best for you. Before making a decision, however, you may want to contact several lawyers or law firms to gather some comparative information."

It is extremely important to trust the lawyer or firm one hires. No lawyer can be expected to win every case, and sometimes the best legal advice may not be exactly what you want to hear."

Mesothelioma is a Deadly Cancer

Mesothelioma is considered to be the most deadly type of cancer that cannot be cured easily and the person who suffers from Mesothelioma do not survive for a long time as the lining of the internal organs like the heart, the lungs and the stomach is affected. This cancer is mainly caused by the exposure to asbestos or materials that contain asbestos. This cancer cannot be detected at an early stage as the symptoms of the disease can be seen only in the developed or the last stage. It is a malignant cancer that is the result of inhaling particles of damaged asbestos in the air which start damaging the lining of the internal organs.

Symptoms of Mesothelioma

The symptoms of Mesothelioma can be detected after 20 to 50 years of exposure. If the lining of the heart or the lungs is damaged then the most common problem that develops is breathing problem. This is due to the accumulation of fluid in the chest, which is known as Pleural Mesothelioma. The symptoms are totally different if the stomach lining is affected. The patient often complains of stomach ache, loses his appetite and other problems develop like problem in the bowel, frequent fever, anemia and other problems. Most of the people take these symptoms lightly and by the time they go to the doctor it is too late. After the disease is detected in most patients survive between 6 to 12 months.

Treatment for Mesothelioma

An effective treatment of this disease depends on several factors like, in which stage the cancer has been detected, what is the age of the patient, how much the cancerous cells have circulated and the general health condition of the patient, that is whether he is suffering from some other disease or not. It has been observed that chemotherapy is the only treatment available for these patients. It uses medicines, chemicals or drugs in a systematic manner to eradicate the cancerous cells. The medicine is either injected directly in the body or administered in pill forms.

In few cases the medicine is directly injected in chest. This is called intrapleural chemotherapy. If the lining of the stomach is affected then the medicine is inserted into the abdomen which is called intra peritoneal chemotherapy. The direct insertion is done to retard the formation of the cancerous cells. Patients are advised before the surgery and after the surgery to minimize the development of the cancerous cell.

The patient has to bear the pain of chemotherapy treatment to be cured and gain longevity or has to meet his end within 6-12 months. Now it is in the hands of the patient whether he will go for chemotherapy and have full faith of recovery.

Screening Tests For Mesothelioma

Mesothelioma is a very rare form of cancer that affects the pleural membranes (coverings of the lungs), the peritoneal membranes (coverings of the abdominal organs) or the pericardium (covering of the heart). Mesothelioma is generally seen in people exposed to asbestos. The tumor often takes years to develop and screening people exposed to asbestos remains the only option for early intervention against this disease. People who have held jobs in the construction, shipbuilding and manufacturing industry need to be screened routinely. The following screening tests can be useful to diagnose mesothelioma.

Imaging:

Imaging tests like a simple chest X-Ray, CT Scans, and Magnetic Resonance Imaging (MRI) are often very useful and they may show thick, nodular masses on the pleural surface.

Needle Biopsies:

Under a local anaesthetic, the doctor will insert a large, hollow needle into the chest cavity. The needle is rotated and withdrawn to collect a sample of the tissue in the process. The sample is then examined in the laboratory for malignant cells. The needle biopsy is only about 40% accurate.

Open Biopsy:

This is one of the most accurate methods to diagnose mesothelioma. A larger tissue sample is often obtained with an open biopsy. However the procedure is performed under general anaesthetic.

Cytology:

Cytology of the pleural fluid has little value in diagnosing mesothelioma and is not routinely performed. Almost 85% of the times cytology is negative or inconclusive despite the presence of mesothelioma. Cytology can be performed in conjunction with a biopsy.

Even with the best screening techniques available today, mesothelioma escapes detection. Early screening and routine screening are crucial in people exposed to asbestos in order to prevent serious consequences. Whilst there are no definite cures yet, the speed at which medicine is making progress a cure for mesothelioma should definitely be around the corner. Till then early detection remains the best possible weapon against this disease. Victims of mesothelioma should take appropriate action against their former employers and should get in touch with lawyers who have experience handling these issues.

Friday, September 12, 2008

Mesothelioma Cancer Treatment

Cancer of the Mesothelium or Mesothelioma as it is popularly called, occurs when the cells of the Mesothelium begin to behave in an unusually manner and attack other tissues and organs that are close by. The cancer cells are likely to spread to other areas of the body. Research has found that a greater portion of Mesothelioma cases start emanate in the pleura.

Mesothelioma is said to be a rare with about two thousand cases reported annually in the U.S. there has however been a steady increase in it occurrence over the last twenty years. Research has also shown that the disease is more prevalent in men and the old the person the greater the risk. It is important to note that both men and women are at risk for this disease.

The major risk factor for this disease includes prolonged asbestos exposure. Asbestos is a mineral fiber used in the construction industry. Approximately seventy-five percent of all cases are attributed to asbestos exposure at work. The greater the exposure to asbestos and the longer the exposure the more likely the disease will develop. There are however persons who have had minimal exposure who have developed Mesothelioma. Also no everyone who has had prolonged exposure develops the disease.

Mesothelioma symptoms sometimes do not show themselves until up to fifty years after being exposed to asbestos. Symptoms include shortness of breath, chest pains, weight loss, abdominal pain, and fever. Once the cancer has moved beyond the Mesothelium patients are likely to experience severe pain, swelling of the face and/or neck, and trouble swallowing.

To diagnose Mesothelioma a biopsy is performed. Once this is done the doctor will perform more tests to determine the stage of the disease. Determining the stage of the disease will assist the doctor is developing a treatment plan.

Mesothelioma is usually treated by way of surgery. If the disease in the stomach or chest part of the chest or stomach lining is removed. A portion of the adjoining tissues is also removed. If the disease is found in the pleura then a lung may have to be removed. Another treatment is radiation therapy which is used to kill the cancer cells and to eradicate the tumor. Chemotherapy is also used. Clinical trials are currently on the way to find new treatments for this disease.

Mesothelioma - Your Questions Answered

Q. What is Mesothelioma?

A. Mesothelioma is a rare but potentially fatal cancer that affects a layer of the body called as mesothelium. Typically mesothelioma develops in the lining of the chest or abdominal cavity. There are three forms of mesothelioma:

1. Pleural mesothelioma. Mesothelioma that affects the coverings of the lungs.
2. Peritoneal mesothelioms. Mesothelioma that affects the covering of the abdominal organs.
3. Pericardial mesothelioma. Mesothelioma that affects the covering of the heart.

Pleural is the most common followed by peritoneal and lastly pericardial.

Q. What are the causes of mesothelioma?

A. Asbestos is the number one cause of mesothelioma. Asbestos is a fine fiber material that is resistant to heat. These fibers when inhaled get into the air passages and then reach the pleural cells. The asbestos injures the pleural cells and this injury leads to either benign or malignant transformation. Asbestos is found in many types of industrial supplies and equipments. Asbestos exposure does not lead to mesothelioma immediately. Often it takes decades before the person manifests the symptoms of the disease. Smoking does not lead to mesothelioma though the risk is more for a smoker exposed to asbestos.

Q. What are the symptoms of mesothelioma?

A. Often mistaken for pneumonia, mesothelioma is very difficult to diagnose based on symptoms alone. The most common symptoms include:

Persistent cough.
Shortness of breath.
Chest pains.
Swelling up of face and neck.
Coughing up blood.
Nausea and vomiting.
Weight loss.
Loss of appetite.

Not everyone exposed to asbestos will develop mesothelioma. However keep in mind the risk of asbestos exposure and mesothelioma and speaking to a doctor will help in screening and early detection of the disease.

Q. What treatment options are available for mesothelioma?

A. Mesothelioma is often a very difficult disease to diagnose and treat. The various treatment options include:

Surgery in early stages to reduce tumor burden.
Chemotherapy with agents like Cisplatin.
Radiotherapy.
Gene therapy.
Immunotherapy.
Photodynamic therapy.

Mesothelioma - A Type of Cancer

Mesothelioma is considered to be the most deadly type of cancer that is caused by inhaling the asbestos particles that float in the air. Mostly people who are directly or sometimes indirectly exposed to asbestos contact this disease. It affects the mesothelium which is the protective lining of most the internal organs in the body. Malignant cells develop on the mesothelium of the heart, lungs or the stomach. The mesothelium of the chest cavity and the lungs is known as pleura, the stomach lining is called peritoneum and pericardium is the lining of the heart. There is provision in the law for the compensation of Mesothelioma patients and special lawyers called asbestos lawyers help the patients in their legal pursuit.

Symptoms of Mesothelioma

The symptoms of Mesothelioma occur at the last stage of the disease so curing it becomes very difficult. The symptoms can be seen after a long time of exposure to asbestos which may be a long gap of twenty to fifty years. The main symptoms are breathlessness due to accumulation of fluid in the chest, coughing, pain in the chest; blood may also appear with the cough or the spit. These symptoms can be seen if the pleura or the pericardium is affected. If the peritoneum is affected the patient will develop loss of appetite, pain in the stomach, loss of weight, problem in the bowel, anemia and fatigue. The patient may also suffer from frequent fever.

Treatment of Mesothelioma

An effective treatment of this disease depends on several factors like, in which stage the cancer has been detected, what is the age of the patient, how much the cancerous cells have circulated and the general health condition of the patient, that is whether he is suffering from some other disease or not. It has been observed that chemotherapy is the only treatment available for these patients. It uses medicines, chemicals or drugs in a systematic manner to eradicate the cancerous cells. The medicine is either injected directly in the body or administered in pill forms.

The other forms of treatment are immunotherapy, surgery and radiation by which the malignant cells are destroyed so that they do not spread to the other parts of the body. In severe cases many tumors may be detected on the affected area for this the doctors first remove the tumors by surgery and then the other forms of treatment follow. The patient has to decide whether he will undergo the painful treatment or survive for six to twelve months without treatment.

Wednesday, September 10, 2008

Mesothelioma - A Blunder If Not Diagnosed

Mesothelioma is just one of the diseases that people can develop after prolonged asbestos exposure. It is a type of cancer that affects the mesothelial cells which cover the outer surface of most of the body's internal body organs. This is caused by the exposure to asbestos which was around quite a lot in certain areas before it was banned. It could have been contracted in a number of ways from simply breathing it in to picking it up second hand from other people's clothing, hair or skin.

Mesothelioma can take various different forms and can develop in the tissues covering the lungs or abdomen. The most common type diagnosed is pleural mesothelioma which affects the tissues lining the lungs, called the pleura. Fortunately, it is unusual for this disease to spread to other parts of the body. When it does, it doesn't usually cause any problematic symptoms.

Most people who develop mesothelioma will have worked in jobs where they inhaled asbestos particles. The most commonly affected trades were dockers, roofers, plumbers, electricians, shipyard workers and power station workers. However, it is possible for someone to contract the illness even if they have never had direct asbestos exposure. For example, family members may have breathed in the dust particles from the clothing of someone who worked with it.

There are various different symptoms that people can look out for if they know there is a chance they could have mesothelioma. Shortness of breath, a prolonged cough, chest pain, weight loss, abdominal swelling and fever are just some of the signs to look out for. These symptoms may not start showing until 20 to 50 years after asbestos exposure, however which is why many people don't realize what it is at the time.

Diagnosing mesothelioma can be very difficult because the symptoms are similar to many other conditions. For this reason it is extremely important that doctors are made aware of any history to asbestos exposure so they know what to look out for. In order to make a proper diagnosis, a physical examination, a chest x - ray and lung function tests will be performed in order to see if there is any pleural thickening, which is common among those who worked around asbestos. If anything suspicious is found a biopsy will be performed so that a diagnosis can be confirmed and treatment can begin.

Many people have enlisted the help of an asbestos lawyer in order to claim compensation against asbestos manufacturers. The first lawsuit was in 1929 and since then people have successfully won billions of dollars from these companies who neglected to implement safety measures to protect workers against exposure. Mesothelioma Attorneys often take some good percentage of the compensation so watch out before you go ahead and hire any one.

Mesothelioma and Litigation - How to Get Cash For Asbestos Lung Cancer Palliative Care

Mesothelioma is a particularly nasty form of lung cancer, and mesothelioma litigation is increasingly being used as a means of getting cash for asbestos lung cancer palliative care. Without it, many families would not be able to afford professional care for their loved ones, and would have to tend for them themselves at the worst possible time for them and for the patient.

Incidences of mesothelioma asbestos lung cancer are steadily increasing, which indicates just how insidious this disease is. Caused by inhalation of asbestos fibers, the symptoms can take upwards of 40 years after exposure to appear, and may people who suffer do not even remember being exposed to the substance. It does not take much exposure, and many cannot understand the diagnosis when it is available because they cannot remember ever being exposed to asbestos.

There are no known 100% effective conventional medical treatments for mesothelioma, and the prognosis is generally bad. However, there are several things that can be done to alleviate pain and make the patient's life more comfortable. While drugs can help, hospice care is an option that takes pressure of the family and provides a comfortable environment for the patient. However, these alternatives can be expensive and if responsibility can be placed on an employer for the exposure that ultimately led to the disease, then compensation can pay for the palliative care.

This is not seeking charity, but rather making those responsible pay for the treatment. A high level of compensation will be needed to pay for the treatment and care needed, and in order to achieve this result you will require the services of a good mesothelioma attorney. Any lawyer will not do due to the specialized knowledge needed to persuade judges and juries that there very few causes of asbestos lung cancer other than exposure to the fibrous silicates that make up asbestos.

The compensation awarded can be very large, although smokers will receive less since their habit can be construed as contributing to the disease. Mesothelioma is not just another word for asbestos cancer, but is in fact a cancer of the mesothelium, a membrane that lines many body cavities, including the thoracic, or chest cavity. The lining of the lungs is called the pleura, so mesothelioma refers to any form of lung cancer involving that membrane. In fact 80% of mesothelioma cases are caused by smoking.

It is therefore very difficult for smokers to blame asbestos exposure for mesothelioma unless they have been working with asbestos. However, a good asbestos attorney should be able to secure a reasonable level of compensation, even for a smoker. It will be a fight though, since the asbestos companies and employers that required employees to work with the substance are aware of the high levels of compensation being awarded, and now actively fight such cases.

When you consult a law firm with a view to instructing them to fight your mesothelioma case, you should insist on talking with the attorney that will be handling your case. You can then discuss your strategy, and you can make sure that your attorney has had previous success with such cases. You don't want to retain a loser!

Ask questions, and determine the success rate of your prospective attorney in such cases. He or she must also appreciate your condition and understand how you feel, so that they can fight your case properly. Nothing can beat experience in a mesothelioma asbestos cancer lawsuit, so make sure that you get the best you can afford. Better still: tell them their fee depends upon them winning!

Next Door Mesothelioma

Peritoneal mesothelioma, the rarer of the two forms, can lead to swelling, abdominal pain due to fluid buildup in the abdomen cavity, weight. The other more common pleural mesothelioma symptoms include chest pain and difficulty breathing. Other symptoms often noted among patients include weight loss, fever, cough and night sweats. Also occasionally a patient may be diagnosed with pleural mesothelioma before any symptoms manifest.

A misdiagnosed disease is often an opportunity for the disease to grow in the body. The only way to diagnose mesothelioma is to take a series of tests to discover if the disease is present. A common minimum link to determine the disease is finding the patients proximity to asbestos related environment for 15 - 50 years. If so then image scans can help diagnose the disease. Commonly these include taking a chest x-ray which will show a picture of the lungs to determine if there are any abnormal changes.

A CT scan, computer tomography, is a type of x-ray that uses a computer rather than film to display its images. It can be used to show three-dimensional representations of the relevant parts of the body.

The final type of imaging that may be used is an MRI scan, or magnetic resonance imaging. In an MRI, magnetism is used in conjunction with the computer to create clear images of your body.

If your doctor finds an unusual mass during the imaging process, they are most likely going to take a tissue sample (biopsy), or draw fluid from it to determine what type of tissue it is. Typically a needle is used to draw a small amount of fluid from the tissue. If the results are not able to rule out the condition completely, the next step would normally be to insert a small tube which is attached to a camera and to take a small piece of the tissue remotely. In some cases a more extensive surgical procedure may be needed in order to get a good sample of the tissue. The extreme complicated nature of the disease and fatal nature of the disease often arouses fear in a patients mind.

Monday, September 8, 2008

Lung Cancer Treatment -- Photodynamic Therapy Offers a Safe Alternative

Photodynamic therapy (PDT) is one of the newer lung cancer treatment options available today. Lung cancers are sometimes inoperable, particularly when they are situated in the bronchi or trachea. Similarly, cancers that have spread from other parts of the body to the bronchi cannot be removed surgically. In such cases, photodynamic therapy offers a safe and effective treatment option.

In a best-case scenario, PDT is used as a curative therapy that can eliminate the cancer completely. In many patients, PDT is employed as a palliative lung cancer treatment meant to provide relief from symptoms even though it does not cure the cancer.

Photodynamic therapy can effectively relieve symptoms like breathing difficulties from obstructions in the bronchi or trachea. In some patients, tumors block the airways and can cause coughing, breathing difficulties, pneumonia and bleeding. PDT may be used in such cases depending on the location, size and stage of the tumor.

PDT destroys cancer cells using a laser. To ensure that only cancerous cells are destroyed, a special drug is used to make the cancer cells more sensitive to this treatment while leaving normal cells intact.

There are three steps involved in the process of lung cancer treatment using PDT. In stage one, a drug called photofrin is injected intravenously. This drug has the property of making body cells very sensitive to light. Normal, healthy cells eliminate photofrin, but cancerous cells are unable to do so and the drug is retained in such cells.

In the second stage of PDT, about forty to fifty hours after the injection is given, a flexible tube is inserted into the bronchia. This tube contains a red laser of low intensity. The cancer cells exposed to this laser are destroyed.

In the third and final stage, about two days after the laser light exposure, a bronchoscopy is done to get rid of the dead cancer cells and mucus from the bronchi or trachea.

A patient can benefit from photodynamic therapy only if his or her cancer is situated in a location that is accessible to a bronchoscope. Also, the tumor must be large enough so that the bronchoscope can easily detect it. This means that some cancers like those located outside the bronchial passages cannot be treated with PDT.

Lung cancer treatment with PDT offers almost no dangerous side effects, unlike other treatment methods. Photosensitivity is about the only side effect that lasts for a while. Since photofrin makes cells sensitive to light, the patient may experience heightened light sensitivity for a period of four to eight weeks after the treatment.

During this time, even normal exposure to sunlight can result in severe sunburn. For this reason, patients who have undergone PDT are advised not to venture out into the sun for about eight weeks after their lung cancer treatment. In contrast to photodynamic therapy, major surgery done to eliminate lung cancer usually poses much greater risks.

Many tumors that are inoperable because of their location are prime candidates for treatment with PDT. When used as a palliative, this type of lung cancer treatment offers almost immediate relief.

Given all these advantages, increasing numbers of patients have been using photodynamic therapy as a lung cancer treatment of choice.

Important Facts About Lung Cancer

According to the American Cancer Society, lung cancer is still one of the most prevalent forms of cancer today. Even after all of the thousands of antismoking campaigns and a huge decrease in the number of smokers, it is expected that there will be more than 215,000 new cases diagnosed this year, and there will be nearly 162,000 deaths.

In 1991 (the latest year that I could find statistics for), 27% of Americans were smokers. That compares to 29% in 1987 and 44% in 1964. The decrease is because of more people quitting the smoking habit, and NOT because of fewer people starting the smoking habit. It's obvious that all of the efforts to prevent people from becoming smokers have not been successful.

Cigarette smoking is considered the number one cause of the disease. There are substances in smoke that cause damage to lung cells. Because of this, smoking cigarettes, pipes, or cigars does cause lung cancer, and this is why it is also true that secondhand smoke can cause lung cancer in nonsmokers. The more often a person is exposed to tobacco smoke, the greater the risk of lung cancer.

However, cigarette smoking is not the only cause. Researchers have also determined that exposure to radon is a big risk factor for developing lung cancer. Radon is found in mines as well as in various parts of the country in the rock and soil. Radon is a radioactive gas that is colorless, odorless, and tasteless.

Exposure to asbestos is another cause of lung cancer. People who work at such jobs in the construction and chemical industries are most at risk for exposure to asbestos that can cause lung cancer.

A family history of lung cancer, even in people who have never smoked, also creates a higher risk for developing the disease.

What is Lung Cancer - Incidence, Signs, Symptoms, Causation, Prognosis and Treatment

INTRODUCTION

Lung cancer may also be the most tragic cancer because in most cases, it might have been prevented, 87% of lung cancer cases are caused by smoking. Lung cancer has long been the most common cause of cancer death in men and since 1987 it has also become the most common cause of cancer death in women. Lung cancer is the second most commonly occurring form of cancer in most western countries and although the lung cancer incidence is less common in developing countries, the rapid increase in the popularity of smoking will see the number of lung cancer sufferers in those countries quickly catch up with the western world.

Lung cancers can arise in any part of the lung, and 90%-95% of cancers of the lung are thought to arise from the epithelial, or lining cells of the larger and smaller airways (bronchi and bronchioles); for this reason, lung cancers are sometimes called bronchogenic carcinomas or bronchogenic cancers.

The most common type of lung cancers are epidermoid carcinoma, small cell carcinoma, adenocarcinoma and large cell carcinoma.

Most experts agree that lung cancer is attributable to inhalation of carcinogenic pollutants by a susceptible host. Who is most susceptible? Any smoker over the age of 40, especially if they began smoking before the age of 15, have smoked 20 or more for 20 years, or worked with or near asbestos. Two other factors also increase susceptibility: exposure to carcinogenic industrial and air pollutants (asbestos, uranium, arsenic, nickel, iron oxides, chromium, radio active dust, and coal dust.) and familial susceptibility.

SIGNS AND SYMPTOMS

Because early lung cancer usually produces no symptoms, the disease is often in an advanced stage when first diagnosed. Late stage signs are: with epidermoid and small cell carcinoma; smokers cough, hoarseness, wheezing, dyspnea, hemoptysis and chest pain. With adenocarcinoma and large cell carcinoma; fever, weakness, weight loss, anorexia and shoulder pain. In addition, hormone production which regulates various body functions may also be affected.

DIAGNOSIS

Firm diagnosis requires chest x rays, sputum cytology, CT scanning, bronchoscopy the examination of pleural fluid and biopsies. Other tests to detect metastasis include bone scans, bone marrow biopsy and CT scans of the brain and abdomen.

METASTASES

Lung cancer most often spreads to the liver, the adrenal glands, the bones, and the brain. Lung cancer that has metastasized to the bone causes bone pain, usually in the backbone (vertebrae), the thighbones, and the ribs. Lung cancer that spreads to the brain can cause difficulties with vision and weakness on one side of the body.

Lung cancer may grow into certain nerves in the neck, causing a droopy eyelid, small pupil, sunken eye, and reduced perspiration on one side of the face; together these symptoms are called Horner's syndrome (see Autonomic Nervous System Disorders: Horner's Syndrome). Lung cancer may grow directly into the esophagus, or it may grow near it and put pressure on it, leading to difficulty in swallowing. Lung cancer may also spread through the bloodstream to the liver, brain, adrenal glands, spinal cord, and bone.

TREATMENT

Treatment for lung cancer depends on the cancer's specific cell type, how far it has spread, and the patient's performance status. If investigations confirm lung cancer, CT scan and often positron emission tomography (PET) are used to determine whether the disease is localised and amenable to surgery or whether it has spread to the point where it cannot be cured surgically. Treatment is usually a combination of surgery, chemotherapy and radiation therapy.

Surgery is usually the first option. Chemotherapy can be used as a first line treatment for lung cancer or as additional treatment after surgery. Radiation therapy can be directed at your lung cancer from outside your body (external beam radiation) or it can be put inside needles, seeds or catheters and placed inside your body near the cancer (brachytherapy). Radiation therapy can be used alone or along with other lung cancer treatments. Radiation therapy can also be used to lessen side effects of lung cancer.

Treatment may not be as effective for patients with bone or liver metastases from lung cancer, excessive weight loss, ongoing cigarette use, or pre-existing medical conditions such as heart disease or emphysema. At some point, if you and your oncologist or primary care physician agree that treatment no longer is advisable, hospice care can provide comfort.

Early Symptoms of Lung Cancer

Knowing and understanding the early symptoms of lung cancer is one of the most important things that those who are at risk for the disease can do. Lung cancer is the most treatable when it is discovered early, and the only way to discover it early enough is to recognize and report the early symptoms of lung cancer. If you are noticing a combination of these lung cancer symptoms, be sure to talk to your doctor.

One of the early symptoms of lung cancer is a nagging cough that simply will not get better. Often the cough worsens with time and is accompanied by chronic chest pain. Coughing up blood is another of the many early symptoms of lung cancer. In fact, coughing up blood is one of the biggest symptoms that sends lung cancer patients to their doctors. Recurring bronchitis or pneumonia sometimes indicates that the disease is present. Fatigue and shortness of breath are more symptoms to watch out for if you suspect the disease. No matter what the symptoms are, if you have lung cancer, they will gradually progress in intensity as the disease progresses.

These lung cancer symptoms do not always indicate that the disease is present. There are other far less dangerous conditions that can cause these symptoms. However, ignoring the symptoms is dangerous, because if they are pointing to lung cancer, the disease will continue to progress. Early treatment is the best way to successfully fight lung cancer, so do not ignore these symptoms.

Friday, September 5, 2008

OSHA and Modern Asbestos Regulations

The use of asbestos for relatively modern industrial purposes dates back over a century, though partial knowledge of its dangers has existed for thousands of years. Despite concerns raised by medical doctors and scientists in the early 20th century, the asbestos industry avoided serious regulation for decades. Though laws like the Clean Air Act of 1970 did help reduce the use of asbestos , obstacles to stricter regulation were present as late as the 1990s, when an appeals court struck down an Environmental Protection Agency (EPA) regulation known as the Asbestos Ban and Phase Out rule. As a result, asbestos-containing products are used and produced even today.

Today, asbestos use and exposure is regulated by several government agencies, including the EPA and the Occupational Safety and Health Administration, otherwise known as OSHA.

Though virtually anyone can be exposed to asbestos, workers in industries such as construction, mining, and shipbuilding are particularly at risk. Furthermore, the families of these workers are also at risk from secondary exposure if precautionary measures are not taken.

According to OSHA, steps which can be taken to prevent excessive exposure to asbestos-containing materials (ACMs) include:

- Limiting the time that workers spend working with or around ACMs

- Separating asbestos-heavy areas from the majority of the workforce

- Installing effective ventilation systems in and around ACMs

- Providing workers with approved protective gear and clothing

- Providing workers with showers to remove asbestos after work

- Educating workers and administrators about the dangers of ACMs

Asbestos and Mesothelioma

Exposure to asbestos, even in small amounts and over a short period of time, can cause a deadly cancer known as mesothelioma. Mesothelioma is a cancer which attacks the mesothelial lining of the lungs, heart, chest, and abdominal cavity, and it is almost always associated with ACMs. In some cases, mesothelioma can take years to show up after exposure to asbestos, but can often kill within 6-12 months of diagnosis.

Though OSHA has set a limit of 100,000 fibers per cubic meter of workplace air, some experts contend that there is no such thing as a "safe" threshold of exposure, and advocate that the United States follow the example of other countries that have banned the use of asbestos entirely.

Lung Cancer Prevention

Is there anybody alive in the United States today who does NOT know that smoking tobacco is the leading cause of lung cancer? Probably not. To avoid that knowledge, you'd have to live under a rock. There isn't any way to absolutely prevent lung cancer, but never smoking or quitting smoking is one way to significantly lower the risk.

There are, however, other risk factors associated with lung cancer that we have no control over at all. There are environmental causes, that we just can't do anything about. Such things as asbestos, radon, arsenic, chromium, nickel, tar, and soot that are commonly found in the workplace can cause lung cancer in people who have never smoked. The United States and other countries are working to control these substances in the workplace and some progress has been made - not enough, but some.

Just plain old air pollution is another cause of lung cancer. The incidence of lung cancer is higher in cities where air pollution is worse.

Studies have shown that a good diet that is high in fruits, vegetables, and whole grains and low in saturated fat, red meat, and preservatives does lower the risk of contracting lung cancer.

Abstaining from alcohol consumption altogether is another way to lower your risk of contracting lung cancer.

Research shows that people who are physically active have at a lower risk for developing lung cancer than those who are sedentary - and this is true even after taking cigarette smoking into account.

Using drugs, vitamins, or other agents to try to reduce the risk of, or delay the development or recurrence of, cancer is called chemoprevention. This is an area that scientists are studying, and there are clinical trials in progress that are testing both natural as well as man-made drugs, but it has not become a standard treatment or therapy.

Causes and Treatment of Mesothelioma

Mesothelioma is a form of lung cancer, predominantly caused by exposure to asbestos fibers. In fact, mesothelioma is a cancer of the mesothelium, the sheath that covers major organs such as the lungs (pleurum), the heart (pericardium) and the abdominal cavity (peritoneum). Pleural mesothelioma is by far the most common kind.

Mesothelioma and Asbestos

When asbestos fibers are inhaled, they become embedded in the lining of the lungs. Due to their small needle-like size, the normal defenses of the body are unable to detect them. Usually, any foreign bodies such as this would either be coughed up, or be removed through a build-up of mucus around them. But nor asbestos. They cause inflammation of the lungs and tissue damage, leading to scarring and coughing. These are the initial symptoms of asbestosis, though asbestosis is not mesothelioma.

No one knows for sure why cancers develop, but once cancerous cells are formed in the pleura, it gradually becomes thicker, and over time restricts breathing and causes shortness of breath and coughing. What is known as 'pleural effusion' occurs, as the fluid of the pleura, designed to lubricate the movement of the lungs against the other organs nearby, builds up and exerts pressure on the lungs. The thickening of the pleura continues as an increasing number of cells become cancerous, until death eventually occurs.

The Effect of Smoking

Although smoking is known to lead to a number of forms of cancer, it does not in itself promote mesothelioma. However, a patient that has been exposed to asbestos, and who also smokes, will be more liable to contract the disease than a non-smoker will. This is why smokers are generally awarded lower sums in compensation than non-smokers with the same condition. However, it would be wrong to state that smoking is a cause of mesothelioma.

It is, however, the cause of many more lung cancer cases than mesothelioma caused by asbestos, and smoking and asbestos together also increase the risk of the patient developing general lung cancer, just as prolonged exposure to asbestos causes more than just mesothelioma. Asbestos lung cancer and mesothelioma are not the same thing.

Symptoms

The major symptoms are shortness of breath, weight loss, nausea and pain. This is true of all forms of mesothelioma, not only pleural mesothelioma. In the case of peritoneal mesothelioma, the abdomen becomes very painful and distended, just as the pleural version causes tightening and swelling in the chest due to pleural effusion. The pressure created can also result in pain, apart from that of the cancer itself.

Diagnosis

If the disease is not diagnosed early, then survival is unlikely. Therefore, any person who has previously worked in the asbestos industry, or has used asbestos in their employment, should make their doctor aware of that fact. They can then be placed on a schedule of regular examinations designed to detect the first signs of the disease. If the condition is detected early enough, most treatments available can be used effectively, and surgery is much more likely to be effective if the area affected is able to be isolated.

If you have contracted the disease, stopping smoking is essential, and you must try to avoid all infections of the lungs and airways. It is possible to have the condition treated, but if diagnosed too late then treatment tends to be palliative, and designed to make the patient as comfortable as possible.

It is essential, therefore, that people that have a history of contact with asbestos inform their physician immediately to make sure that if the symptoms do occur, they are spotted before any lasting harm can be done. Only then will there be a hope of a cure and successful recovery from this insidious disease.

Mesothelioma Law Firm

There are very many mesothelioma law firms around and the main reason why they specialize in these particular cases is the huge return the cases can fetch. Others might be genuinely out there for the compassion of mesothelioma victims but, they are limited. Firstly though, mesothelioma is a cancer that affects the protective lining of the heart, lungs and abdomen. The known cause of mesothelioma is asbestos exposure. This is a natural mineral that has very many industrial uses mainly because of its heat and fire resistant qualities. It is known to lodge in the system when inhaled where it can stay there for many years where finally it causes the emergence of a disease. It has no scent and its fibers in the air are microscopic. Therefore mesothelioma law firms are relevant in the following way.

Firstly, the companies that employ workers to work exposed to asbestos have a case to answer because they have a moral duty to inform workers. They are therefore directly responsible for the illness in their worker. When a mesothelioma victim decides to file a suit against the company, they need to have the representation of good lawyers who can be found in a good mesothelioma law firm. Some of the workers who might be at risk to asbestos exposure include miners, millers, shipyard workers, building construction workers and others. With the serious realization of the dangers posed by asbestos, strict legislations have been put in place to ban certain types of asbestos and also there are restrictions on the amount of asbestos exposed to workers.

Also, workers who are close to asbestos have protective cloths and equipment to protect then from the substance. When they leave work, most workers take a shower and change cloths to avoid contaminating their families. When you suspect that you might be suffering from mesothelioma, you need to visit a doctor for a diagnosis. If you have the disease, you need to take time and look for a reputable mesothelioma law firm which will have good lawyers. They should have some experience in this kinds of cases. They should not live very far from where you are located so that you can reach them with minimal cost. The mesothelioma law firm should be legal and licensed to practice law in your particular state or country. They should give you more information on the cases they have been able to resolve.

On the internet, you will find very many mesothelioma law firms advertising themselves and you should not just take them at face value. You need to contact them and visit their offices to get a first hand feel of what they are all about. Many firms will be literally fighting for your case and you do not have to hire the ones who are first make a perfect pitch. Firstly, you need to know that they can represent you and win the case. You should discuss on the attorney fee before you hire the lawyer from the law firms. Usually, the most common way of payment is through a contingency basis and this means that they will be paid when you win the case. There is no doubt that with the right lawyers on your side, you are certain to get your deserved justice will be served.
 
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